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Hemorrhagic cystitis may develop in patients treated with cyclophosphamideRarelythis condition can be severe and even fatalFibrosis of the urinary bladdersometimes extensivealso may develop with or without accompanying cystitisAtypical urinary bladder epithelial cells may appear in the urineThese adverse effects appear to depend on the dose of cyclophosphamide and the duration of therapySuch bladder injury is thought to be due to cyclophosphamide metabolites excreted in the urineForced fluid intake helps to assure an the blue pill review. ample output of urinenecessitates frequent voidingand reduces the time the drug remains in the bladderThis helps to prevent cystitisHematuria usually resolves in a few days after cyclophosphamide treatment is stoppedbut it may persistMedical and/or surgical supportive treatment may be requiredrarelyto treat protracted cases of severe hemorrhagic cystitisIt is usually necessary to discontinue cyclophosphamide therapy in instances of severe hemorrhagic cystitis.

Cyclophosphamide can cause fetal harm when administered to a pregnant woman and such abnormalities have been reported following cyclophosphamide therapy in pregnant womenAbnormalities were found in two infants and a six-month-old fetus born to women treated with cyclophosphamideEctrodactylia was found in two of the three casesNormal infants have also been born to women treated with cyclophosphamide during pregnancyincluding the first trimesterIf this drug is used during pregnancyor if the patient becomes pregnant while takingreceivingthis drugthe patient should be apprised of the potential hazard to the fetusWomen of childbearing potential should be advised to avoid becoming pregnant.

Continued use of cyclophosphamide is contraindicated in patients with severely depressed bone marrow functionCyclophosphamide is contraindicated in patients who have demonstrated a previous hypersensitivity to itSee WARNINGS and PRECAUTIONS

Cyclophosphamide is available in generic formand you need a prescription to obtain it.

Continued use of cyclophosphamide is contraindicated in patients with severely depressed bone marrow functionCyclophosphamide is contraindicated in patients who have demonstrated a previous hypersensitivity to itSee WARNINGS and PRECAUTIONS

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